![]() By design, as described in the initial National Institutes of Health grant application, those individuals with neither of the main 2 genotype patterns were not included in the main analyses. As described in Stanton et al, 10 of all the possible combinations of variance in 3 single-nucleotide polymorphism multilocus genotype patterns, some were considered consistent with the low-fat genotype pattern, some with the low-carbohydrate genotype pattern, and some with neither of these 2 genotype patterns. ![]() Statistical analyses include data from all individuals randomized (described in the Statistical Analysis section).Ī, Three-way interaction term among diet, genotype, and the 12-month time point was not statistically significant (beta coefficient, 1.38 P = .20). of participants reflect data for the individuals who had weight data at both baseline and 12 months. The black solid circle indicates the mean, the left and right borders of the box mark the first and third quartiles, the black vertical line indicates the median, the error bars indicate the 5th and 95th percentiles, and the hollow circles indicate the individuals whose values were outside the 5th or 95th percentiles.
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